The TA-SMTP-Reputation add-on should install on your Exchange Server hosts without problems as long as you configure it for the version of Windows Server you run before you deploy it.
If you do not configure the add-on for your version of Windows Server before you deploy it, then the add-on only collects data inputs that are common to all supported versions of Windows Server. This results in missing data that is specific to your version of Windows Server.
See Configure TA-SMTP-Reputation for the procedure to configure the add-on and distribute it to your Exchange Server SMTP-Reputation Server hosts.
If you upgrade from an earlier version of the Splunk App for Microsoft Exchange, complete the upgrade instructions in the Splunk App for Microsoft Exchange manual to ensure that the add-on collects all Windows Server data for the version of Windows Server that you run.
This documentation applies to the following versions of Splunk® App for Microsoft Exchange: 3.5.2, 4.0.0, 4.0.1